Research Areas

Patterson and her collaborators are working to address the following three major research questions:

1. How does psychosocial stress & stress resilience impact symptom severity, disease activity, and immune function among individuals living with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE)?

2. How does physical activity impact immune function and clinical outcomes in RA and SLE?

3. How can we apply integrative health treatment approaches to address unmet needs in rheumatology?

Publications

Epigenetic attenuation of interferon signaling is associated with aging-related improvements in systemic lupus erythematosus.

Science translational medicine

Narendra R, Van Phan H, Patterson SL, Almonte-Loya A, Lydon EC, Lanata C, Love C, Park J, Shimoda M, Barcellos L, Mekonen H, Detweiler A, Deosthale P, Neff N, Criswell LA, Maliskova L, Eckalbar W, Fragiadakis GK, Yazdany J, Dall'Era M, Katz P, Ye CJ, Sirota M, Langelier CR
The importance of thinking outside the (medical) box: the impact of lifestyle on the outcomes of rheumatic and musculoskeletal conditions and the promise of lifestyle medicine.

Arthritis care & research

Katz P, Andonian BJ, Patterson SL
Experiences with Complementary and Integrative Health Among People with Rheumatoid Arthritis and Systemic Lupus Erythematosus: A Qualitative Study.

The Journal of rheumatology

Patterson SL, Ruvalcaba D, Issa A, Rai K, Katz P, Koenig CJ
Transcriptomic analysis reveals immune signatures associated with specific cutaneous manifestations of lupus in systemic lupus erythematosus.

bioRxiv : the preprint server for biology

Lee EY, Patterson S, Cutts Z, Lanata CM, Dall'Era M, Yazdany J, Criswell LA, Haemel A, Katz P, Ye CJ, Langelier C, Sirota M
Perceived Stress and Prediction of Worse Patient-Reported Outcomes in a Rheumatoid Arthritis Cohort.

Arthritis care & research

Patterson SL, Park J, Hartogensis W, Katz P
Epigenetic attenuation of interferon signaling drives aging-related improvements in systemic lupus.

medRxiv : the preprint server for health sciences

Narendra R, Phan HV, Patterson SL, Almonte Loya AL, Lanata C, Love C, Park J, Lydon EC, Shimoda MA, Barcellos L, Mekonen H, Detweiler A, Deosthale P, Neff N, Criswell LA, Maliskova L, Eckalbar W, Fragiadakis G, Yazdany J, Dall'Era M, Katz P, Ye CJ, Sirota M, Langelier CR
Physical inactivity exacerbates pathologic inflammatory signalling at the single cell level in patients with systemic lupus.

EBioMedicine

Patterson SL, Van Phan H, Ye CJ, Lanata C, González SC, Park J, Criswell LA, Barbour KE, Yazdany J, Dall'Era M, Sirota M, Katz P, Langelier CR
Cell-Specific Transposable Element and Gene Expression Analysis Across Systemic Lupus Erythematosus Phenotypes.

ACR open rheumatology

Cutts Z, Patterson S, Maliskova L, Taylor KE, Ye CJ, Dall'Era M, Yazdany J, Criswell LA, Fragiadakis GK, Langelier C, Capra JA, Sirota M, Lanata CM
Positive psychosocial factors may protect against perceived stress in people with systemic lupus erythematosus with and without trauma history.

Lupus science & medicine

DeQuattro K, Trupin L, Patterson S, Rush S, Gordon C, Greenlund KJ, Barbour KE, Lanata C, Criswell LA, Dall'Era M, Yazdany J, Katz PP
The association of trauma with self-reported flares and disease activity in systemic lupus erythematosus (SLE).

Rheumatology (Oxford, England)

Katz P, Patterson SL, DeQuattro K, Lanata CM, Barbour KE, Greenlund KJ, Gordon C, Criswell LA, Dall'Era M, Yazdany J